What really causes human obesity?
Duration: 31 mins 46 secs
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Description: |
Lecture given by Dr. Sadaf Farooqi, Clinical Scientist for the Wellcome Trust , Department of Clinical Biochemistry, University of Cambridge who is a Fellow of Trinity College.
The lecture was given at Cambridge in America Day 2007 in San Francisco, Grand Hyatt Union Square, March 31, 2007. |
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Created: | 2008-11-12 15:12 |
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Collection: | Cambridge in America |
Publisher: | University of Cambridge |
Copyright: | University of Cambridge |
Language: | eng (English) |
Keywords: | Obesity; Health; Wellcome; |
Abstract: | Considerable attention has been paid to the secular changes in food intake and physical activity that underlie the recent rise in the prevalence of obesity. However, there is compelling evidence that inter-individual differences in susceptibility to obesity have strong genetic determinants. The molecular and physiological characterization of human obesity syndromes has provided a better mechanistic understanding of the regulation of appetite and body weight in humans, which will have implications for the treatment of obesity and associated metabolic disorders.
Sadaf Farooqi qualified with Honors in Medicine from the University of Birmingham in 1993, and was awarded the Queen's Scholarship (gold medal) for best overall academic performance. Following hospital posts in Birmingham and Oxford, she came to Cambridge as part of a Wellcome Trust Training Fellowship, leading to the award of a PhD in 2001. During this time she identified the first single gene defect to cause human obesity in two children with a mutation in the gene encoding the hormone leptin. |
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