p) Dr Richard Osei-Amponsah (University of Ghana, Legon – CAPREx Fellow) and Dr Carole Sargent (Department of Pathology, Cambridge)

Duration: 19 mins 3 secs

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Description:	Collaborating on researching the ‘genetic diversity and genomic selection of the Ashanti dwarf pig of Ghana'

Created:

2014-11-13 16:44

Collection:

Cambridge-Africa Day 2014

Publisher:

University of Cambridge

Cambridge-Africa Programme

Language:

eng (English)

Keywords:

Africa; Ashanti Dwarf Pig; Genomics; Food Security; Ghana;

Credits:

Person:	Dr Richard Osei-Amponsah
Person:	Dr Carole Sargent
Person:	Professor Nabeel Affara
Editor:	Dr Bjoern Hassler
Author:	Cambridge-Africa


Abstract:	Characterisation of animal genetic resources provides relevant data for their conservation and sustainable use for food security and economic development. A study was carried out to determine the origin and phylogenetic status of the local Ashanti Dwarf Pig (ADP) of Ghana and their crosses with modern commercial breeds based on their mtDNA, MC1R and Y-chromosome sequence polymorphisms. Analyses of MtDNA D loop region and Y chromosome sequences from 146 local pigs revealed that the ADP of Ghana has multiple origins but is more likely to have originated from the European wild boar than its Asian counterpart. The ADP also displays considerable variation in the MC1R gene with black coat colour being the most predominant within the breed. Predominant MC1R alleles found in local pigs of Ghana were the black spotting (EP, 29%) followed by Asian dominant black (ED1, 25%) and European dominant black (ED2, 21%). Within the subset of animals classified as ‘ADP’, the dominant black allele is of Asian origin, although the majority (58%) of MC1R alleles are of European origin. The wide variations in coat colour patterns suggest that morphology alone cannot be used to adequately characterise Ghanaian local pigs. PCA analysis of SNP Ghanaian local pigs. PCA analysis of SNP genotyping data revealed a strong location and breed effect on clustering of local Ghanaian pigs. Funding is being sought for further studies on more local pigs to identify potential signatures for genomic selection find out the effect of admixture on important adaptive and economic traits of the ADP and other local sub species in Africa.

Abstract:

Characterisation of animal genetic resources provides relevant data for their conservation and sustainable use for food security and economic development. A study was carried out to determine the origin and phylogenetic status of the local Ashanti Dwarf Pig (ADP) of Ghana and their crosses with modern commercial breeds based on their mtDNA, MC1R and Y-chromosome sequence polymorphisms. Analyses of MtDNA D loop region and Y chromosome sequences from 146 local pigs revealed that the ADP of Ghana has multiple origins but is more likely to have originated from the European wild boar than its Asian counterpart. The ADP also displays considerable variation in the MC1R gene with black coat colour being the most predominant within the breed. Predominant MC1R alleles found in local pigs of Ghana were the black spotting (EP, 29%) followed by Asian dominant black (ED1, 25%) and European dominant black (ED2, 21%). Within the subset of animals classified as ‘ADP’, the dominant black allele is of Asian origin, although the majority (58%) of MC1R alleles are of European origin. The wide variations in coat colour patterns suggest that morphology alone cannot be used to adequately characterise Ghanaian local pigs. PCA analysis of SNP Ghanaian local pigs. PCA analysis of SNP genotyping data revealed a strong location and breed effect on clustering of local Ghanaian pigs. Funding is being sought for further studies on more local pigs to identify potential signatures for genomic selection find out the effect of admixture on important adaptive and economic traits of the ADP and other local sub species in Africa.

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